Prof Kwadwo completed his medical education in Ghana, obtaining the MB, ChB from the University of Ghana in 1982.  He obtained his graduate training at the University of Tulane (MPH&TM, 1988) the and London School of Hygiene and Tropical Medicine (PhD, 1993).  He worked as a medical officer at the Bawku Hospital, District Medical Officer of Health, Bawku district, Scientific Officer (epidemiology) MRC Unit, Fajara, The Gambia before joining the faculty of the Noguchi Memorial Institute, University of Ghana, as a Research Fellow in Epidemiology in 1993.  At Noguchi Memorial Institute, he has led large scale field epidemiology studies on the epidemiology and control of malaria, including the immune-epidemiology of malaria, epidemiology of drug-resistant infections and also clinical trials of new interventions.  He was promoted Professor of Epidemiology in 2009 and served as the director of the Institute from 2012 – 2017.  He is also an adjunct lecturer in epidemiology at the School of Public Health, University of Ghana, deputy director of the West African Centre for Cell Biology of Infectious Pathogens (WACCBIP) and a visiting professor of tropical medicine at the Tokyo Medical and Dental University.

Kwadwo has published 147 peer-reviewed scientific papers including 142 journal articles, 5 book chapters, 1 patent and edited two books.  He has been an invited speaker at several conferences, including the Multilateral Initiative on Malaria (MIM), Global Health Security Agenda, Rotterdam (2016) among others. He has served on several boards and committees including WHO ad hoc committees on malaria drug efficacy, chair of the Inter Agency Committee on malaria (National Malaria Control Program), scientific committee of the African Malaria Vaccine Network (AMVTN), currently serves as a member of the Scientific Advisory Board of the MRC Unit, Fajara, The Gambia. He is a member of the editorial boards of the Ghana Medical Journal, Tropical Doctor and Malaria Research and Treatment.  He is a member of the Ghana Medical Association, American Society of Tropical Medicine and Hygiene and a fellow of the Ghana College of Physicians and Surgeons (Public Health).